How many institutions own PRAX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PRAX shares is 410, representing 117.55% of the company's common stock.

Who are the major shareholders selling Praxis Precision Medicines, Inc. stock?

ORBIS ALLAN GRAY LTD, in the last quarter, reduced its stake in PRAX by -38.13% restricting it's holding to 1.53 million shares of worth nearly $512.16M. FIRST TRUST ADVISORS LP also lessened -51.74% of the PRAX shares from its portfolio, reducing its holding to 16.09 thousand shares of worth $5.39M. MOODY ALDRICH PARTNERS LLC also shunned PRAX shares holding by -12.09% last quarter which brought its holding to 19.07 thousand shares worth $6.38M.

Investors who are buying PRAX stock?

As per its latest 13F filing, HOOD RIVER CAPITAL MANAGEMENT LLC increased its stake in PRAX by 18.56% in the last quarter. The institutional holder raised its holding to 425.17 thousand shares having worth more than $142.34M. SUSQUEHANNA INTERNATIONAL GROUP, LLP also added 25.48% more shares of PRAX to its portfolio, raising its holding to 125.1 thousand shares of worth $41.88M. DRIEHAUS CAPITAL MANAGEMENT LLC also increased its PRAX shares holding by 1.03% which brought its holding to 959.05 thousand shares worth $321.08M.

PRAX's major insiders: who are they?

The insider with the most stakes in PRAX is N/A , N/A at the company. Additionally, PRAX stock is highly held by N/A N/A and N/A N/A among others.

Did an insider recently sell PRAX stock?

Company executives, directors, and other insiders own 0.28% percent of Praxis Precision Medicines, Inc.'s stock. Within the last six months, there have been 1 transaction(s) in which PRAX insiders have sold stock, totaling 837 shares. Insiders that have sold shares include DESIMONE JILL, MASTROCOLA LAUREN, and NEMIROFF ALEX.

Which insider recently purchased PRAX stock?

There have been 0 transaction(s) during the past 6-months in which Praxis Precision Medicines, Inc. insiders have bought stock, totalling 0 shares

How much of PRAX does insiders own?

Around 2.34K Praxis Precision Medicines, Inc. shares are held by insiders, which represents about 0.28% of PRAX stock.

Who is the insider with the largest stake?

PRAX N/A, N/A holds the largest portfolio of the company's shares. PRAX shares owned by N/A total nearly -.

Which institution holds the most shares in PRAX?

HOOD RIVER CAPITAL MANAGEMENT LLC is the largest institutional owner in PRAX which holds 425.17 thousand shares worth $142.34M or 1.46% of the total PRAX shares outstanding followed by SUSQUEHANNA INTERNATIONAL GROUP, LLP with ownership of 125.1 thousand shares representing 0.43% of the PRAX ownership. ORBIS ALLAN GRAY LTD is the third largest stakeholder with 1.53 million shares or 5.25% of the ownership worth more than $512.16M.

Is Praxis Precision Medicines, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PRAX is concerned, it is a stock which is optionable.

Is there a short position on PRAX's shares?

Number of PRAX shares short is 3.66M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PRAX shares are there?

As of today, 27.92M shares of PRAX are outstanding.

Is there many float in PRAX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PRAX has 24.08M shares in float.

PRAX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PRAX is 9.56.

Praxis Precision Medicines (PRAX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares13.12

Short Percent Of Float13.15

Shares Outstanding27.92M

Shares Float24.08M

Shares Short3.66M

Short Ratio9.56

13.15%

Short % of Float

13.12%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.28% Percentage of Shares held by All Insiders

117.55% Percentage of Shares held by All Institutions

117.88% Percentage of Float held by Institutions

410

Number of Institutions Holding Shares

Institutional Ownership

About 117.55% of PRAX shares are held by financial institutions. HOOD RIVER CAPITAL MANAGEMENT LLC is the top corporate investor, holding 425.17K shares valued at $142.34M. A 1.46% stake in Praxis Precision Medicines, Inc. is owned by the company. SUSQUEHANNA INTERNATIONAL GROUP, LLP owns 125.1K shares valued at $41.88M, which translates its holding of 0.43% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Jun 30, 2026	HOOD RIVER CAPITAL MANAGEMENT LLC	1.46%	425.17K	142.34M	66.55K	+18.56%
Jun 30, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.43%	125.1K	41.88M	25.4K	+25.48%
Jun 30, 2026	ORBIS ALLAN GRAY LTD	5.25%	1.53M	512.16M	-942.69K	-38.13%
Jun 30, 2026	DRIEHAUS CAPITAL MANAGEMENT LLC	3.29%	959.05K	321.08M	9.82K	+1.03%
Jun 30, 2026	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.31%	963.35K	322.52M	0	0
Jun 30, 2026	NORTHERN TRUST CORP	0.83%	240.89K	80.65M	12.95K	+5.68%
Jun 30, 2026	PICTET ASSET MANAGEMENT HOLDING SA	1%	291.69K	98.04M	5.05K	+1.76%
Jun 30, 2026	FRANKLIN RESOURCES INC	1.12%	327.12K	109.52M	51K	+18.47%
Jun 30, 2026	NORGES BANK	1.19%	346.97K	116.16M	346.97K	+100.00%
Jun 30, 2026	VANGUARD CAPITAL MANAGEMENT LLC	4.24%	1.24M	413.57M	13.36K	+1.09%
Jun 30, 2026	BNP PARIBAS ARBITRAGE, SNC	0.65%	188.41K	63.08M	45.33K	+31.68%
Jun 30, 2026	WESTFIELD CAPITAL MANAGEMENT CO LP	0.75%	218.9K	73.28M	218.24K	+32,966.16%
Jun 30, 2026	AMERICAN CENTURY COMPANIES INC	0.81%	237.32K	79.45M	109.06K	+85.04%
Jun 30, 2026	GEODE CAPITAL MANAGEMENT, LLC	2.57%	748.04K	250.48M	97.14K	+14.92%
Jun 30, 2026	MORGAN STANLEY	2.93%	854.11K	285.95M	20.62K	+2.47%
Jun 30, 2026	STATE STREET CORP	3.52%	1.03M	343.66M	142.21K	+16.08%
Jun 30, 2026	FIRST TRUST ADVISORS LP	0.06%	16.09K	5.39M	-17.25K	-51.74%
Jun 30, 2026	VANGUARD PORTFOLIO MANAGEMENT LLC	4.58%	1.34M	447.01M	578.44K	+76.44%
Jun 30, 2026	ALGERT GLOBAL LLC	0.06%	17.48K	5.85M	1.31K	+8.10%
Jun 30, 2026	MOODY ALDRICH PARTNERS LLC	0.07%	19.07K	6.38M	-2.62K	-12.09%
Jun 30, 2026	PRUDENTIAL FINANCIAL INC	0.07%	19.54K	6.54M	-10.97K	-35.95%
Jun 30, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.08%	22.63K	7.58M	634	+2.88%
Jun 30, 2026	NUVEEN, LLC	0.37%	108.03K	36.17M	35.99K	+49.95%
Jun 30, 2026	MARSHALL WACE, LLP	0.47%	137.01K	45.87M	91.86K	+203.46%
Jun 30, 2026	VERITION FUND MANAGEMENT LLC	0.69%	201.1K	67.33M	201.1K	+100.00%
Jun 30, 2026	CITIGROUP INC	0.08%	23.6K	7.9M	17.95K	+317.98%
Jun 30, 2026	WCM INVESTMENT MANAGEMENT, LLC	0.09%	24.74K	8.67M	24.74K	+100.00%
Jun 30, 2026	PEREGRINE CAPITAL MANAGEMENT LLC	0.09%	25.79K	8.63M	25.79K	+100.00%
Jun 30, 2026	CAPITAL FUND MANAGEMENT S.A.	0.09%	27.06K	9.06M	27.06K	+100.00%
Jun 30, 2026	TD ASSET MANAGEMENT INC	0.09%	27.16K	9.09M	-7.98K	-22.72%
Jun 30, 2026	CLEARBRIDGE INVESTMENTS, LLC	0.1%	27.98K	9.37M	27.98K	+100.00%
Jun 30, 2026	DIMENSIONAL FUND ADVISORS LP	0.11%	31.57K	10.57M	413	+1.33%
Jun 30, 2026	PERCEPTIVE ADVISORS LLC	6.99%	2.04M	681.63M	0	0
Jun 30, 2026	RHUMBLINE ADVISERS	0.11%	32.35K	10.83M	-532	-1.62%
Jun 30, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	36.19K	12.12M	-1.96K	-5.13%
Jun 30, 2026	JPMORGAN CHASE & CO	0.15%	44.09K	15.81M	-36.1K	-45.02%
Jun 30, 2026	ARROWMARK COLORADO HOLDINGS LLC	0.16%	46.03K	15.41M	-71.82K	-60.94%
Jun 30, 2026	SWISS NATIONAL BANK	0.16%	46.1K	15.43M	-600	-1.28%
Jun 30, 2026	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.17%	48.12K	16.11M	686	+1.45%
Jun 30, 2026	RUSSELL INVESTMENTS GROUP, LTD.	0.18%	51.03K	17.09M	27.92K	+120.81%
Jun 30, 2026	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.2%	56.84K	19.03M	56.84K	+100.00%
Jun 30, 2026	VOYA INVESTMENT MANAGEMENT LLC	0.42%	122.23K	40.92M	94.09K	+334.45%
Jun 30, 2026	CANDRIAM S.C.A.	0.21%	60.86K	20.35M	-2.77K	-4.36%
Jun 30, 2026	DEUTSCHE BANK AG\	0.22%	64.26K	21.51M	6.48K	+11.22%
Jun 30, 2026	BAKER BROS. ADVISORS LP	6.02%	1.75M	586.95M	0	0
Jun 30, 2026	SILVERARC CAPITAL MANAGEMENT, LLC	0.23%	65.68K	21.99M	-5.87K	-8.21%
Jun 30, 2026	BANK OF NEW YORK MELLON CORP	0.3%	85.38K	28.58M	-1.67K	-1.92%
Jun 30, 2026	NEUBERGER BERMAN GROUP LLC	0.31%	89.47K	29.95M	63.51K	+244.64%
Jun 30, 2026	BLACKROCK, INC.	7.87%	2.29M	767.53M	-32.34K	-1.39%
Jun 30, 2026		4.62%	1.34M	447.01M	578.44K	+76.44%
Jun 30, 2026	BANK OF AMERICA CORP /DE/	1.88%	546.93K	183.11M	12.33K	+2.31%
Jun 30, 2026	INVESCO LTD.	1.85%	537.55K	179.97M	476.15K	+775.53%
Jun 30, 2026	ABRDN PLC	0.57%	166.4K	55.71M	-6.09K	-3.53%
Jun 30, 2026	ADAGE CAPITAL PARTNERS GP, L.L.C.	3.49%	1.02M	339.97M	199.74K	+24.49%
Jun 30, 2026	GOLDMAN SACHS GROUP INC	1.88%	548.83K	183.74M	-161.9K	-22.78%
Jun 30, 2026	CORMORANT ASSET MANAGEMENT, LP	2.2%	640K	214.27M	-245.5K	-27.72%
Jun 30, 2026	PRICE T ROWE ASSOCIATES INC /MD/	3.24%	943K	315.71M	312.15K	+49.48%
Jun 30, 2026	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.37%	107.41K	35.96M	100.02K	+1,353.83%
Jun 30, 2026	JUPITER TOPCO LLC	11.74%	3.42M	1.15B	3.42M	+100.00%
Jun 30, 2026	FMR LLC	7.95%	2.32M	775.68M	155.96K	+7.22%
Jun 30, 2026	683 CAPITAL MANAGEMENT, LLC	0.38%	110.4K	36.96M	-2.3K	-2.04%
Jun 30, 2026	WELLINGTON MANAGEMENT GROUP LLP	0.43%	125.87K	42.14M	-48.48K	-27.81%
Jun 30, 2026	UBS GROUP AG	0.45%	131.05K	43.87M	22.6K	+20.84%
Jun 30, 2026	QUBE RESEARCH & TECHNOLOGIES LTD	0.52%	152.48K	51.05M	24.25K	+18.91%
Jun 30, 2026	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.55%	160.48K	53.73M	-14.76K	-8.42%
Jun 30, 2026	SOLEUS CAPITAL MANAGEMENT, L.P.	0.61%	177.52K	59.43M	-153K	-46.29%
Jun 30, 2026	AFFINITY ASSET ADVISORS, LLC	0.64%	185K	61.94M	15K	+8.82%
Jun 30, 2026	VANGUARD FIDUCIARY TRUST CO	0.65%	188.16K	62.99M	18.26K	+10.75%
Jun 30, 2026	WOODLINE PARTNERS LP	0.69%	200.01K	66.96M	0	0
Jun 30, 2026	SIXTH STREET PARTNERS MANAGEMENT COMPANY, L.P.	0.76%	220.01K	73.66M	220.01K	+100.00%
Jun 30, 2026	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.76%	220.01K	73.66M	4.56K	+2.12%
Jun 30, 2026	CAPTION MANAGEMENT, LLC	0.77%	224.8K	75.26M	24.8K	+12.40%
Jun 30, 2026	ORBIMED ADVISORS LLC	0.79%	230.1K	77.04M	57.6K	+33.39%
Jun 30, 2026	LOGOS GLOBAL MANAGEMENT LP	0.89%	260K	87.05M	-25K	-8.77%
Jun 30, 2026	VIVO CAPITAL, LLC	0.93%	271.12K	90.77M	-67.78K	-20.00%
Jun 30, 2026	POLAR CAPITAL HOLDINGS PLC	0.96%	279.13K	93.45M	279.13K	+100.00%
Mar 31, 2026	RA CAPITAL MANAGEMENT, L.P.	1.29%	373.79K	120.43M	0	0
Mar 31, 2026	SOLEUS CAPITAL MANAGEMENT, L.P.	1.14%	330.52K	106.49M	-32.45K	-8.94%
Mar 31, 2026	NUVEEN, LLC	0.25%	72.04K	23.21M	22.07K	+44.17%
Mar 31, 2026	ORBIS ALLAN GRAY LTD	8.56%	2.47M	796.61M	1.22M	+96.98%
Mar 31, 2026	STATE STREET CORP	3.06%	884.24K	284.89M	2.02K	+0.23%
Mar 31, 2026	MORGAN STANLEY	2.89%	833.49K	268.54M	-56.4K	-6.34%
Mar 31, 2026	ARROWMARK COLORADO HOLDINGS LLC	0.41%	117.85K	37.97M	87.85K	+292.84%
Mar 31, 2026	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.61%	175.24K	56.46M	-101.16K	-36.60%
Mar 31, 2026	CAPTION MANAGEMENT, LLC	0.69%	200K	64.44M	0	0
Mar 31, 2026	WOODLINE PARTNERS LP	0.69%	200.01K	64.44M	94.6K	+89.74%
Mar 31, 2026	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.75%	215.45K	69.41M	17.15K	+8.65%
Mar 31, 2026	FRANKLIN RESOURCES INC	0.96%	276.12K	88.96M	-79.95K	-22.45%
Mar 31, 2026	QUBE RESEARCH & TECHNOLOGIES LTD	0.44%	128.23K	41.31M	-40.67K	-24.08%
Mar 31, 2026	AMERICAN CENTURY COMPANIES INC	0.44%	128.25K	41.32M	52.89K	+70.17%
Mar 31, 2026	BNP PARIBAS ARBITRAGE, SNC	0.5%	143.08K	46.1M	138.46K	+2,993.00%
Mar 31, 2026	VANGUARD FIDUCIARY TRUST CO	0.59%	169.9K	54.74M	169.9K	+100.00%
Mar 31, 2026	AFFINITY ASSET ADVISORS, LLC	0.59%	170K	54.77M	-15K	-8.11%
Mar 31, 2026	ABRDN PLC	0.6%	172.48K	55.57M	37.49K	+27.77%
Mar 31, 2026	ORBIMED ADVISORS LLC	0.6%	172.5K	55.58M	78K	+82.54%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	0.6%	174.35K	56.17M	-2.21K	-1.25%
Mar 31, 2026	LOGOS GLOBAL MANAGEMENT LP	0.99%	285K	91.82M	-90K	-24.00%
Mar 31, 2026	PICTET ASSET MANAGEMENT HOLDING SA	0.99%	286.64K	91.43M	46.06K	+19.14%
Mar 31, 2026	BANK OF AMERICA CORP /DE/	1.85%	534.6K	172.24M	11.84K	+2.27%
Mar 31, 2026	PRICE T ROWE ASSOCIATES INC /MD/	2.18%	630.85K	203.26M	-155.14K	-19.74%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	2.25%	650.9K	209.75M	88.53K	+15.74%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	2.46%	710.73K	228.99M	-5.45K	-0.76%
Mar 31, 2026	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.35%	100.78K	32.47M	0	0
Mar 31, 2026	UBS GROUP AG	0.38%	108.45K	34.94M	19.25K	+21.58%
Mar 31, 2026	683 CAPITAL MANAGEMENT, LLC	0.39%	112.7K	36.31M	-57.1K	-33.63%
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0.05%	11.61K	3.74M	-13.62K	-53.98%
Mar 31, 2026	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.06%	12.47K	4.02M	12.47K	+100.00%
Mar 31, 2026	ALLIANZ ASSET MANAGEMENT GMBH	0.06%	14.03K	4.52M	11.63K	+484.58%
Mar 31, 2026	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.07%	14.74K	4.75M	14.74K	+100.00%
Mar 31, 2026	ALGERT GLOBAL LLC	0.07%	16.17K	5.21M	-64.47K	-79.95%
Mar 31, 2026	CREATIVE PLANNING	0.07%	16.29K	5.25M	5.44K	+50.20%
Mar 31, 2026	LEGAL & GENERAL GROUP PLC	0.08%	18.48K	5.95M	501	+2.79%
Mar 31, 2026	EAM INVESTORS, LLC	0.08%	19K	6.12M	-1.95K	-9.29%
Mar 31, 2026	MOODY ALDRICH PARTNERS LLC	0.1%	21.69K	6.99M	-20.04K	-48.03%
Mar 31, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.1%	22K	7.09M	22K	+100.00%
Mar 31, 2026	RUSSELL INVESTMENTS GROUP, LTD.	0.1%	23.11K	7.45M	2.5K	+12.13%
Mar 31, 2026	CONGRESS ASSET MANAGEMENT CO /MA	0.11%	24.84K	8M	-6.41K	-20.50%
Mar 31, 2026	UNIVERSITY OF WISCONSIN FOUNDATION	0.11%	25.22K	8.12M	25.22K	+100.00%
Mar 31, 2026	NEUBERGER BERMAN GROUP LLC	0.12%	25.96K	8.36M	282	+1.10%
Mar 31, 2026	VOYA INVESTMENT MANAGEMENT LLC	0.13%	28.13K	9.06M	14.48K	+106.03%
Mar 31, 2026	SEI INVESTMENTS CO	0.13%	29.53K	9.51M	13.73K	+86.91%
Mar 31, 2026	LORD, ABBETT & CO. LLC	0.13%	29.62K	9.54M	-1.14K	-3.70%
Mar 31, 2026	PRUDENTIAL FINANCIAL INC	0.14%	30.51K	9.83M	15.65K	+105.29%
Mar 31, 2026	DIMENSIONAL FUND ADVISORS LP	0.14%	31.16K	10.04M	7.62K	+32.36%
Mar 31, 2026	RHUMBLINE ADVISERS	0.15%	32.88K	10.59M	4.56K	+16.08%
Mar 31, 2026	FIRST TRUST ADVISORS LP	0.15%	33.34K	10.74M	-55.37K	-62.42%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.16%	35.15K	11.32M	-11K	-23.84%
Mar 31, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	38.15K	12.29M	2.86K	+8.10%
Mar 31, 2026	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.19%	42.16K	13.58M	42.16K	+100.00%
Mar 31, 2026	SWISS NATIONAL BANK	0.21%	46.7K	15.05M	6.2K	+15.31%
Mar 31, 2026	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.21%	47.43K	15.28M	10.06K	+26.90%
Mar 31, 2026	JANE STREET GROUP, LLC	0.21%	46.9K	15.11M	-26.9K	-36.45%
Mar 31, 2026	DEUTSCHE BANK AG\	0.26%	57.78K	18.62M	6.97K	+13.71%
Mar 31, 2026	INVESCO LTD.	0.27%	61.4K	19.78M	-15.69K	-20.35%
Mar 31, 2026	CANDRIAM S.C.A.	0.28%	63.63K	20.5M	-46.96K	-42.47%
Mar 31, 2026	ENSIGN PEAK ADVISORS, INC	0.3%	68.38K	22.03M	4.1K	+6.38%
Mar 31, 2026		2.62%	756.75K	243.82M	756.75K	+100.00%
Mar 31, 2026	BLACKROCK, INC.	8.05%	2.32M	749.07M	246.43K	+11.86%
Mar 31, 2026	ALYESKA INVESTMENT GROUP, L.P.	0.25%	72.18K	23.26M	-2.2K	-2.96%
Mar 31, 2026	BAKER BROS. ADVISORS LP	6.07%	1.75M	564.86M	626.71K	+55.63%
Mar 31, 2026	IKARIAN CAPITAL, LLC	0.25%	71.58K	23.06M	-15K	-17.32%
Mar 31, 2026	DRIEHAUS CAPITAL MANAGEMENT LLC	3.29%	949.23K	305.83M	16.16K	+1.73%
Mar 31, 2026	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.34%	963.35K	310.38M	60K	+6.64%
Mar 31, 2026	PERCEPTIVE ADVISORS LLC	7.05%	2.04M	655.97M	40K	+2.00%
Mar 31, 2026	JANUS HENDERSON GROUP PLC	11.98%	3.46M	1.11B	218.78K	+6.75%
Mar 31, 2026	JPMORGAN CHASE & CO	0.28%	80.18K	22.17M	24.88K	+44.99%
Mar 31, 2026	METLIFE INVESTMENT MANAGEMENT, LLC	0.28%	80.93K	26.07M	68.51K	+551.40%
Mar 31, 2026	BANK OF NEW YORK MELLON CORP	0.3%	87.05K	28.05M	9.15K	+11.75%
Mar 31, 2026	ACUTA CAPITAL PARTNERS, LLC	0.29%	84.9K	27.35M	1.87K	+2.25%
Mar 31, 2026	VIVO CAPITAL, LLC	1.17%	338.9K	109.19M	10K	+3.04%
Mar 31, 2026	HOOD RIVER CAPITAL MANAGEMENT LLC	1.24%	358.62K	115.54M	69.15K	+23.89%
Mar 31, 2026	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.82%	815.74K	262.82M	-149.57K	-15.49%
Mar 31, 2026	CORMORANT ASSET MANAGEMENT, LP	3.07%	885.5K	285.3M	-64.5K	-6.79%
Mar 31, 2026	FMR LLC	7.48%	2.16M	696.23M	802.27K	+59.05%
Mar 31, 2026	VANGUARD CAPITAL MANAGEMENT LLC	4.23%	1.22M	393.7M	1.22M	+100.00%
Mar 31, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.35%	99.7K	32.12M	-51K	-33.84%
Mar 31, 2026	SILVERARC CAPITAL MANAGEMENT, LLC	0.32%	71.55K	23.05M	-10.91K	-13.23%
Mar 31, 2026	NORTHERN TRUST CORP	0.79%	227.93K	73.44M	35.65K	+18.54%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	12.42K	3.66M	1.9K	+18.10%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.06%	13.66K	4.02M	13.66K	+100.00%
Dec 31, 2025	BLACKROCK, INC.	9.46%	2.08M	612.62M	277.42K	+15.40%
Dec 31, 2025	WOODLINE PARTNERS LP	0.48%	105.41K	31.07M	-312.26K	-74.76%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.24%	492.35K	145.11M	-1M	-67.09%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.58%	785.99K	231.66M	-217.5K	-21.67%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.91%	200K	58.95M	56.5K	+39.37%
Dec 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.32%	289.47K	85.32M	289.47K	+100.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.77%	168.9K	49.78M	111.59K	+194.74%
Dec 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.77%	169.8K	50.05M	169.8K	+100.00%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.8%	176.56K	52.04M	115.32K	+188.31%
Dec 31, 2025	EMPOWERED FUNDS, LLC	0.17%	36.85K	10.86M	36.85K	+100.00%
Dec 31, 2025	CANDRIAM S.C.A.	0.5%	110.59K	32.6M	47.72K	+75.91%
Dec 31, 2025	EXOME ASSET MANAGEMENT LLC	0.26%	58.12K	17.13M	-43.87K	-43.02%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.34%	74.38K	21.92M	-67.14K	-47.44%
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.11%	903.35K	266.25M	62.5K	+7.43%
Dec 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	4.25%	933.06K	275.01M	432.51K	+86.41%
Dec 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0.38%	83.04K	24.47M	33.29K	+66.90%
Dec 31, 2025	FIRST TRUST ADVISORS LP	0.4%	88.7K	26.14M	59.74K	+206.23%
Dec 31, 2025	UBS GROUP AG	0.41%	89.2K	26.29M	-7.61K	-7.86%
Dec 31, 2025	ORBIMED ADVISORS LLC	0.43%	94.5K	27.85M	94.5K	+100.00%
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.57%	125.72K	37.06M	-47.11K	-27.26%
Dec 31, 2025	ABRDN PLC	0.61%	134.99K	39.79M	134.99K	+100.00%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.84%	185K	54.53M	185K	+100.00%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.9%	198.3K	58.45M	36.64K	+22.66%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.09%	240.59K	71.09M	240.59K	+100.00%
Dec 31, 2025	FRANKLIN RESOURCES INC	1.62%	356.07K	104.95M	41.92K	+13.34%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.65%	362.97K	106.98M	-496.2K	-57.75%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	1.71%	375K	110.53M	250K	+200.00%
Dec 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	1.86%	408.79K	120.49M	-992	-0.24%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.11%	23.54K	6.94M	-13.87K	-37.07%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.11%	25.24K	7.44M	11.63K	+85.48%
Dec 31, 2025	NEUBERGER BERMAN GROUP LLC	0.12%	25.68K	7.57M	25.68K	+100.00%
Dec 31, 2025	SEI INVESTMENTS CO	0.07%	15.8K	4.66M	15.8K	+100.00%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.07%	16.01K	4.72M	16.01K	+100.00%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.08%	17.98K	5.3M	1.16K	+6.88%
Dec 31, 2025	EAM INVESTORS, LLC	0.1%	20.94K	6.17M	20.94K	+100.00%
Dec 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.1%	22.95K	6.76M	22.95K	+100.00%
Dec 31, 2025	RHUMBLINE ADVISERS	0.13%	28.32K	8.35B	1.53K	+5.71%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.13%	28.83K	8.5M	6.92K	+31.61%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.14%	30.76K	9.07M	30.76K	+100.00%
Dec 31, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.14%	31.25K	9.21M	807	+2.65%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.15%	33.29K	9.86M	-2.54K	-7.08%
Dec 31, 2025	CITADEL ADVISORS LLC	0.16%	34.92K	10.29B	27.12K	+347.77%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.16%	35.29K	10.4M	11.53K	+48.54%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.16%	35.75K	10.54M	35.75K	+100.00%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.17%	37.38K	11.02M	37.38K	+100.00%
Dec 31, 2025	SWISS NATIONAL BANK	0.18%	40.5K	11.94M	5K	+14.08%
Dec 31, 2025	MOODY ALDRICH PARTNERS LLC	0.19%	41.73K	12.3M	41.73K	+100.00%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.21%	46.15K	13.6M	5.26K	+12.87%
Dec 31, 2025	DIADEMA PARTNERS LP	0.46%	100.6K	29.65M	600	+0.60%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.39%	86.58K	25.52M	58.01K	+203.04%
Dec 31, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.21%	46.46K	13.69M	46.46K	+100.00%
Dec 31, 2025	NUVEEN, LLC	0.23%	49.97K	14.73M	11.42K	+29.63%
Dec 31, 2025	DEUTSCHE BANK AG\	0.23%	50.81K	14.98M	36.96K	+266.71%
Dec 31, 2025	JPMORGAN CHASE & CO	0.25%	55.3K	16.3M	29.09K	+111.00%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.29%	64.28K	18.95M	64.28K	+100.00%
Dec 31, 2025	72 INVESTMENT HOLDINGS, LLC	0.3%	65.93K	19.43M	0	0
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.3%	66.23K	19.52M	66.23K	+100.00%
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.31%	67.1K	19.78M	67.1K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	0.32%	69.24K	20.41M	1.1K	+1.62%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.69%	150.7K	44.42M	69.1K	+84.68%
Dec 31, 2025	JANE STREET GROUP, LLC	0.22%	48.7K	14.35B	32.5K	+200.62%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.35%	77.9K	22.96M	21.61K	+38.39%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	2.38%	522.76K	154.08M	39.9K	+8.26%
Dec 31, 2025	BARCLAYS PLC	2.42%	530.75K	156.43M	454.11K	+592.55%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.56%	562.38K	165.78M	105.35K	+23.05%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	3.26%	716.18K	211.09M	123.16K	+20.77%
Dec 31, 2025	STATE STREET CORP	4.01%	882.22K	260.02M	-24.89K	-2.74%
Dec 31, 2025	MORGAN STANLEY	4.05%	889.89K	262.29M	246.39K	+38.29%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	4.32%	950K	280M	-50K	-5.00%
Dec 31, 2025	VIVO CAPITAL, LLC	1.5%	328.9K	96.94M	130K	+65.36%
Dec 31, 2025	VANGUARD GROUP INC	6.65%	1.46M	430.6M	193.65K	+15.28%
Dec 31, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.46%	100.78K	29.7M	-32.02K	-24.11%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	1.7%	373.79K	110.17M	373.79K	+100.00%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.34%	75.37K	22.21M	60.1K	+393.62%
Dec 31, 2025	EAGLE HEALTH INVESTMENTS LP	0.07%	14.95K	4.41M	14.95K	+100.00%
Dec 31, 2025	ALGERT GLOBAL LLC	0.37%	80.64K	23.77M	-80.18K	-49.86%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.38%	82.47K	24.31M	31.26K	+61.03%
Dec 31, 2025	NORTHERN TRUST CORP	0.87%	192.28K	56.67M	23.93K	+14.21%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.23%	276.39K	81.46M	276.39K	+100.00%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	9.08%	2M	588.3M	431.43K	+27.58%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.39%	965.31K	284.52M	-1.41M	-59.34%
Dec 31, 2025	BAKER BROS. ADVISORS LP	5.13%	1.13M	332.02M	437K	+63.38%
Dec 31, 2025	ORBIS ALLAN GRAY LTD	5.71%	1.26M	369.95M	1.26M	+100.00%
Dec 31, 2025	FMR LLC	6.18%	1.36M	400.46M	1.32M	+3,044.28%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	14.74%	3.24M	954.83M	476.23K	+17.23%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	8.73K	2.57M	980	+12.64%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.05%	9.97K	2.94M	-3.53K	-26.16%
Dec 31, 2025	ERSTE ASSET MANAGEMENT GMBH	0.05%	10.5K	3.2M	10.5K	+100.00%
Sep 30, 2025	HUSSMAN STRATEGIC ADVISORS, INC.	0.05%	10.5K	556.5K	0	0
Sep 30, 2025	VANGUARD GROUP INC	5.9%	1.27M	67.17M	51.64K	+4.25%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.26%	56.4K	2.99M	-32.5K	-36.56%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.26%	56.29K	2.98M	3.74K	+7.11%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.24%	51.21K	2.71M	41.21K	+412.10%
Sep 30, 2025	ACUTA CAPITAL PARTNERS, LLC	0.23%	49.75K	2.64M	-24.34K	-32.85%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	4.66%	1M	53M	-625K	-38.46%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	4%	859.17K	45.54M	-107.57K	-11.13%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.92%	840.85K	44.57M	153.92K	+22.41%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.44%	95K	5.04M	27.71K	+41.19%
Sep 30, 2025	BLACKROCK, INC.	8.39%	1.8M	95.46M	210.95K	+13.27%
Sep 30, 2025	CIBC ASSET MANAGEMENT INC	1.81%	388.76K	20.6M	0	0
Sep 30, 2025	FRANKLIN RESOURCES INC	1.46%	314.16K	16.65M	7	0.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.78%	168.35K	8.92M	-45.36K	-21.22%
Sep 30, 2025	FMR LLC	0.2%	43.21K	2.29M	5.11K	+13.41%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.19%	40.88K	2.17M	-23.05K	-36.06%
Sep 30, 2025	NUVEEN, LLC	0.18%	38.55K	2.04M	0	0
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.17%	37.57K	1.99M	12.77K	+51.47%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.17%	37.41K	1.98M	37.41K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.17%	35.5K	1.88M	4.7K	+15.26%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.15%	32.19K	1.71M	32.19K	+100.00%
Sep 30, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.14%	30.44K	1.61M	30.44K	+100.00%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.13%	28.97K	1.54M	28.97K	+100.00%
Sep 30, 2025	KNOTT DAVID M JR	0.13%	28K	1.48M	28K	+100.00%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.13%	27K	1.43M	0	0
Sep 30, 2025	RHUMBLINE ADVISERS	0.12%	26.79K	1.42M	-547	-2.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.12%	26.21K	1.39M	12.27K	+88.03%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.1%	22.53K	1.19M	-2.8K	-11.05%
Sep 30, 2025	INVESCO LTD.	0.1%	20.87K	1.11M	4.93K	+30.92%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.08%	16.82K	891.67K	154	+0.92%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.08%	16.63K	881.28M	16.63K	+100.00%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.07%	15.27K	809.2K	15.27K	+100.00%
Sep 30, 2025	PCG WEALTH ADVISORS, LLC	0.07%	14.48K	767.6K	14.48K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.06%	13.86K	734.37K	1.73K	+14.29%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	13.61K	721.07K	2.35K	+20.91%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.06%	13.5K	715K	13.5K	+100.00%
Sep 30, 2025	HSBC HOLDINGS PLC	0.05%	11.17K	594.69K	11.17K	+100.00%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	10.52K	557.56K	0	0
Sep 30, 2025	ALPS ADVISORS INC	0.05%	10.42K	552.47K	-570	-5.18%
Sep 30, 2025	PROFUND ADVISORS LLC	0.04%	8.08K	428.19K	2.82K	+53.56%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	7.75K	410.96K	-965	-11.07%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0.03%	7.13K	377.84K	6.5K	+1,033.39%
Sep 30, 2025	PHOENIX HOLDINGS LTD.	0.03%	6.82K	361.52K	6.82K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	6.6K	349.8K	0	0
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.03%	5.74K	304K	-6.27K	-52.20%
Sep 30, 2025	CERITY PARTNERS LLC	0.03%	5.45K	288.85K	-161	-2.87%
Sep 30, 2025	ARIZONA STATE RETIREMENT SYSTEM	0.03%	5.42K	287.1K	5.42K	+100.00%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	4.92K	260.5K	1.13K	+29.72%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	12.87%	2.76M	146.48M	230.45K	+9.10%
Sep 30, 2025	MORGAN STANLEY	3%	643.5K	34.11M	-582.84K	-47.53%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	2.76%	593.02K	31.43M	367.03K	+162.41%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.38%	81.6K	4.32M	-21.2K	-20.62%
Sep 30, 2025	BARCLAYS PLC	0.36%	76.64K	4.06M	-12.09K	-13.62%
Sep 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.35%	76.22K	4.04M	5.77K	+8.20%
Sep 30, 2025	TRI LOCUM PARTNERS LP	0.35%	75.99K	4.03M	-119.45K	-61.12%
Sep 30, 2025	MARSHALL WACE, LLP	0.32%	68.14K	3.61M	68.14K	+100.00%
Sep 30, 2025	72 INVESTMENT HOLDINGS, LLC	0.31%	65.93K	3.49M	0	0
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	2.33%	500.55K	26.53M	-30.44K	-5.73%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	2.25%	482.86K	25.59M	29.46K	+6.50%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	11.06%	2.37M	125.83M	399.5K	+20.23%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	7.29%	1.56M	82.92M	811.63K	+107.80%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	6.97%	1.5M	79.29M	541.91K	+56.80%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	4.67%	1M	53.19M	-469.59K	-31.88%
Sep 30, 2025	STATE STREET CORP	4.22%	907.11K	48.08M	209.02K	+29.94%
Sep 30, 2025	BAKER BROS. ADVISORS LP	3.21%	689.49K	36.54M	0	0
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.13%	457.03K	24.23M	5.3K	+1.17%
Sep 30, 2025	WOODLINE PARTNERS LP	1.94%	417.67K	22.14M	371.72K	+808.92%
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	1.91%	409.78K	21.72M	-194.52K	-32.19%
Sep 30, 2025	VIVO CAPITAL, LLC	0.93%	198.9K	10.54M	31.3K	+18.67%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.8%	172.83K	9.16M	157.12K	+999.66%
Sep 30, 2025	5AM VENTURE MANAGEMENT, LLC	0.79%	170K	9.01M	0	0
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.75%	161.66K	8.57M	9.22K	+6.05%
Sep 30, 2025	ALGERT GLOBAL LLC	0.75%	160.82K	8.52M	133.25K	+483.31%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.67%	143.5K	7.61M	143.5K	+100.00%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.66%	141.52K	7.5M	16.52K	+13.21%
Sep 30, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.62%	132.81K	7.04M	-16.53K	-11.07%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.58%	125K	6.63M	-100K	-44.44%
Sep 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.51%	109.18K	5.79M	109.18K	+100.00%
Sep 30, 2025	EXOME ASSET MANAGEMENT LLC	0.48%	102K	5.41M	42.99K	+72.87%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.47%	100K	5.3M	-142.4K	-58.75%
Sep 30, 2025	ALLY BRIDGE GROUP (NY) LLC	0.47%	100K	5.3M	100K	+100.00%
Sep 30, 2025	DIADEMA PARTNERS LP	0.47%	100K	5.3M	100K	+100.00%
Sep 30, 2025	UBS GROUP AG	0.45%	96.81K	5.13M	10.28K	+11.88%
Sep 30, 2025	CANDRIAM S.C.A.	0.29%	62.87K	3.33M	-805	-1.26%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.29%	61.24K	3.25M	5.36K	+9.59%
Sep 30, 2025	PFM HEALTH SCIENCES, LP	0.28%	60.58K	3.21M	-24.14K	-28.49%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.27%	57.9K	3.07M	-51.86K	-47.25%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.27%	57.3K	3.04M	57.3K	+100.00%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	1.05%	225K	9.46M	225K	+100.00%
Jun 30, 2025	IKARIAN CAPITAL, LLC	1.13%	242.4K	10.19M	242.4K	+100.00%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.2%	686.93K	28.89M	67K	+10.81%
Jun 30, 2025	UBS OCONNOR LLC	0.1%	21.89K	920.56K	-4.9K	-18.29%
Jun 30, 2025	ROYAL BANK OF CANADA	0.11%	22.59K	950K	22.49K	+20,819.44%
Jun 30, 2025	FMR LLC	0.18%	38.1K	1.6B	2.38K	+6.67%
Jun 30, 2025	72 INVESTMENT HOLDINGS, LLC	0.31%	65.93K	2.77M	0	0
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.58%	125K	5.26M	-25K	-16.67%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	4.5%	966.74K	40.65M	-173K	-15.18%
Jun 30, 2025	MORGAN STANLEY	5.71%	1.23M	51.57B	12.67K	+1.04%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	7.57%	1.63M	68.33M	-120K	-6.88%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	2.47%	530.99K	22.33M	49.39K	+10.26%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	2.81%	604.3K	25.41M	96.9K	+19.10%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	3.51%	752.92K	31.66M	-227.97K	-23.24%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	4.44%	954.08K	40.12M	620.54K	+186.05%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.41%	88.9K	3.74M	88.9K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.48%	102.8K	4.32M	-18.2K	-15.04%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.45%	96.95K	4.08M	9.86K	+11.33%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.47%	100K	4.21M	0	0
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.39%	84.71K	3.56M	-76.15K	-47.34%
Jun 30, 2025	UBS GROUP AG	0.4%	86.53K	3.64M	-106.38K	-55.14%
Jun 30, 2025	BARCLAYS PLC	0.41%	88.72K	3.73M	56.96K	+179.29%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.71%	152.44K	6.41M	11.36K	+8.06%
Jun 30, 2025	TRI LOCUM PARTNERS LP	0.91%	195.43K	8.22M	111.77K	+133.61%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.46%	314.15K	13.21M	23	+0.01%
Jun 30, 2025	CIBC ASSET MANAGEMENT INC	1.81%	388.76K	16.35M	0	0
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.1%	451.73K	19M	33.72K	+8.07%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	2.11%	453.4K	19.07M	-7.3K	-1.59%
Jun 30, 2025	BAKER BROS. ADVISORS LP	3.21%	689.49K	28.99M	357.96K	+107.97%
Jun 30, 2025	STATE STREET CORP	3.25%	698.09K	29.35M	-38.95K	-5.28%
Jun 30, 2025	NOMURA HOLDINGS INC	0.09%	20.2K	849.41K	0	0
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.11%	23.87K	1.01M	12.17K	+103.90%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	24.81K	1.04M	-4.44K	-15.18%
Jun 30, 2025	ALLY BRIDGE GROUP (NY) LLC	0.38%	80.88K	3.4M	-14.7K	-15.38%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.47%	100.7K	4.23M	94.63K	+1,557.92%
Jun 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.13%	27K	1.14M	27K	+100.00%
Jun 30, 2025	ALGERT GLOBAL LLC	0.13%	27.57K	1.16M	6.08K	+28.29%
Jun 30, 2025	STEMPOINT CAPITAL LP	0.15%	32.26K	1.36M	32.26K	+100.00%
Jun 30, 2025		0.16%	35K	1.47M	16K	+84.21%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.72%	369.25K	15.53M	-33.75K	-8.37%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.07%	15.72K	660.9K	-141.92K	-90.03%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.07%	14.76K	620.62K	148	+1.01%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.18%	39.04K	1.64M	20.76K	+113.54%
Jun 30, 2025	WOODLINE PARTNERS LP	0.21%	45.95K	1.93M	-129.78K	-73.85%
Jun 30, 2025	CANDRIAM S.C.A.	0.3%	63.67K	2.68M	0	0
Jun 30, 2025	ABRDN PLC	1%	214.06K	9M	126.15K	+143.51%
Jun 30, 2025	SKOPOS LABS, INC.	0%	298	12.53K	298	+100.00%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	445	18.71K	427	+2,372.22%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	787	33.09K	112	+16.59%
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.01%	2.09K	87.8K	-228	-9.84%
Jun 30, 2025	QUARRY LP	0.02%	4.8K	201.84K	900	+23.08%
Jun 30, 2025	MAVEN SECURITIES LTD	0.02%	5K	210.25K	5K	+100.00%
Jun 30, 2025	CERITY PARTNERS LLC	0.03%	5.61K	235.94K	5.61K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.03%	5.75K	241.79K	5.75K	+100.00%
Jun 30, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.04%	8.5K	357.55K	8.5K	+100.00%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	8.72K	366.63K	-79	-0.90%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.05%	10K	420.5K	-156.07K	-93.98%
Jun 30, 2025	SIG BROKERAGE, LP	0.05%	10K	420.5K	0	0
Jun 30, 2025	HUSSMAN STRATEGIC ADVISORS, INC.	0.05%	10.5K	441.53K	0	0
Jun 30, 2025	ALPS ADVISORS INC	0.05%	10.99K	462.3K	-3.94K	-26.40%
Jun 30, 2025	BLACKROCK, INC.	7.4%	1.59M	66.86M	173.19K	+12.22%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	9.19%	1.97M	83.03M	231.83K	+13.30%
Jun 30, 2025	PRELUDE CAPITAL MANAGEMENT, LLC	0.09%	19.9K	836.8K	19.9K	+100.00%
Jun 30, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.7%	149.33K	6.28M	-35.67K	-19.28%
Jun 30, 2025	5AM VENTURE MANAGEMENT, LLC	0.79%	170K	7.15M	0	0
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.05%	225.99K	9.5B	48.73K	+27.49%
Jun 30, 2025	NORTHERN TRUST CORP	1%	213.71K	8.99M	48.53K	+29.38%
Jun 30, 2025	VANGUARD GROUP INC	5.66%	1.22M	51.12M	128.62K	+11.83%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	6.86%	1.47M	61.94M	377.35K	+34.44%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	11.8%	2.53M	106.52M	1.03M	+68.17%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.3%	63.94K	2.69M	26.8K	+72.16%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.31%	67.29K	2.83M	28K	+71.28%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.55%	118.48K	4.98M	-81.18K	-40.66%
Jun 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.33%	70.45K	2.96M	5.18K	+7.94%
Jun 30, 2025	VIVO CAPITAL, LLC	0.78%	167.6K	7.05M	167.6K	+100.00%
Jun 30, 2025	ACUTA CAPITAL PARTNERS, LLC	0.35%	74.09K	3.12M	-13.05K	-14.98%
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	0.35%	74.3K	3.12M	-20K	-21.21%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.37%	79.14K	3.33M	555	+0.71%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.41%	87.08K	3.3M	68.47K	+367.80%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.63%	131.76K	4.99M	42.14K	+47.03%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.67%	141.08K	5.34M	-1.81K	-1.27%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.69%	145.5K	5.51M	145.5K	+100.00%
Mar 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.71%	150K	5.68M	-76.79K	-33.86%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.75%	157.64K	5.97M	157.64K	+100.00%
Mar 31, 2025	PFM HEALTH SCIENCES, LP	0.76%	160.87K	6.09M	41.36K	+34.61%
Mar 31, 2025	NORTHERN TRUST CORP	0.78%	165.18K	6.26M	-2.41K	-1.44%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.79%	166.07K	6.29M	93.56K	+129.02%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	0.81%	170K	6.44M	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	0.83%	175.73K	6.65M	165.78K	+1,666.46%
Mar 31, 2025	UBS GROUP AG	0.92%	192.91K	7.31M	72.64K	+60.40%
Mar 31, 2025	VERITION FUND MANAGEMENT LLC	0.95%	199.66K	7.56M	-264.85K	-57.02%
Mar 31, 2025	CIBC ASSET MANAGEMENT INC	1.85%	388.76K	14.72M	22K	+6.00%
Mar 31, 2025	VR ADVISER, LLC	4.7%	989.99K	37.49M	0	0
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.2%	1.1M	41.5M	-112.8K	-9.33%
Mar 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0.41%	87.14K	3.3M	19.64K	+29.10%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.91%	403K	15.26M	403K	+100.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	2.19%	460.71K	17.45M	455.2K	+8,270.40%
Mar 31, 2025	ABRDN PLC	0.42%	87.9K	3.33M	82.9K	+1,658.41%
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.45%	94.3K	3.57M	94.3K	+100.00%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	2.29%	481.6K	18.24M	316.69K	+192.03%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.37%	78.59K	2.98M	33.16K	+73.00%
Mar 31, 2025	ALLY BRIDGE GROUP (NY) LLC	0.45%	95.58K	3.62M	50.6K	+112.49%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.47%	100K	3.79M	17K	+20.48%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.53%	110.8K	4.2M	26.5K	+31.44%
Mar 31, 2025	FRANKLIN RESOURCES INC	1.49%	314.13K	11.9M	-75.71K	-19.42%
Mar 31, 2025	BAKER BROS. ADVISORS LP	1.57%	331.53K	12.56M	0	0
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.94%	619.93K	23.48M	619.93K	+100.00%
Mar 31, 2025	STATE STREET CORP	3.5%	737.04K	27.91M	-31.62K	-4.11%
Mar 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	4.05%	853.75K	32.33M	-139.82K	-14.07%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	4.66%	980.89K	37.15M	-348.84K	-26.23%
Mar 31, 2025	VANGUARD GROUP INC	5.16%	1.09M	41.17M	23.38K	+2.20%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	5.41%	1.14M	43.16M	896.2K	+367.99%
Mar 31, 2025	MORGAN STANLEY	5.76%	1.21M	45.96M	50.14K	+4.31%
Mar 31, 2025	BLACKROCK, INC.	6.73%	1.42M	53.66M	-45.51K	-3.11%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	7.15%	1.51M	58.35M	576.91K	+62.07%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	8.28%	1.74M	66M	1.14M	+188.05%
Mar 31, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.88%	185K	7.01M	-115K	-38.33%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.99%	418.02K	15.83M	11.31K	+2.78%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	2.41%	507.4K	19.22M	-51.68K	-9.24%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	8.29%	1.75M	66.08M	51.78K	+3.06%
Mar 31, 2025	TRI LOCUM PARTNERS LP	0.4%	83.66K	3.17M	46.39K	+124.47%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.58%	333.53K	12.63M	-187.74K	-36.02%
Mar 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.53%	112.5K	4.26M	112.5K	+100.00%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.54%	113.7K	4.31M	74.9K	+193.04%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.84%	177.26K	6.71M	-102.13K	-36.55%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0%	0	-	-75.08K	-100.00%
Dec 31, 2023	BLACKROCK INC.	0%	0	-	-1.87M	-100.00%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	0%	0	-	-33.55K	-100.00%
Dec 31, 2023	KINGDON CAPITAL MANAGEMENT, L.L.C.	0%	0	-	-5.2M	-100.00%
Dec 31, 2023	TORONTO DOMINION BANK	0%	0	-	-400	-100.00%
Dec 31, 2023	GROUP ONE TRADING, L.P.	0%	0	-	-2.65K	-100.00%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0%	0	-	-1.43M	-100.00%
Dec 31, 2023	MORGAN STANLEY	0%	0	-	-290.21K	-100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0%	0	-	-92.61K	-100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	0	-	-21.15K	-100.00%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0%	0	-	-683.38K	-100.00%
Dec 31, 2023	CITIGROUP INC	0%	0	-	-83.12K	-100.00%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0%	0	-	-21.12K	-100.00%
Dec 31, 2023	FMR LLC	0%	0	-	-1.93K	-100.00%
Dec 31, 2023	VANGUARD GROUP INC	0%	0	-	-5.56M	-100.00%
Dec 31, 2023	STATE STREET CORP	0%	0	-	-206.56K	-100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0%	0	-	-296.01K	-100.00%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	0	-	-938	-100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	0	-	-4.17M	-100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	0	-	-1.47K	-100.00%
Dec 31, 2023	BOOTHBAY FUND MANAGEMENT, LLC	0%	0	-	-453.15K	-100.00%
Dec 31, 2023	ACUTA CAPITAL PARTNERS, LLC	0%	0	-	-4.49M	-100.00%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	0%	0	-	-9.5M	-100.00%
Dec 31, 2023	MARSHALL WACE, LLP	0%	0	-	-626.67K	-100.00%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0%	0	-	-182.5K	-100.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0%	0	-	-1.3M	-100.00%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0%	0	-	-56.9K	-100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0%	0	-	-8.78M	-100.00%
Dec 31, 2023	PRUDENTIAL FINANCIAL INC	0%	0	-	-16.7K	-100.00%
Dec 31, 2023	UBS OCONNOR LLC	0%	0	-	-583.54K	-100.00%
Dec 31, 2023	PRINCIPAL FINANCIAL GROUP INC	0%	0	-	-34.65K	-100.00%
Dec 31, 2023	RHUMBLINE ADVISERS	0%	0	-	-2.29K	-100.00%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0%	0	-	-201.7K	-100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0%	0	-	-12.57K	-100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-977K	-100.00%
Dec 31, 2023	CIBC ASSET MANAGEMENT INC	0%	0	-	-1.83M	-100.00%
Dec 31, 2023	DEUTSCHE BANK AG\	0%	0	-	-2.29K	-100.00%
Dec 31, 2023	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-37.8K	-100.00%
Dec 31, 2023	PFM HEALTH SCIENCES, LP	0%	0	-	-8.92M	-100.00%
Dec 31, 2023	ZUCKERMAN INVESTMENT GROUP, LLC	0%	0	-	-10.48K	-100.00%
Dec 31, 2023	CITADEL ADVISORS LLC	0%	0	-	-22.2K	-100.00%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0%	0	-	-56.13K	-100.00%
Dec 31, 2023	BAKER BROS. ADVISORS LP	0.1%	131.53K	2.93M	-1.75M	-93.00%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.24%	328.99K	7.33M	-4.52M	-93.22%
Dec 31, 2023	J. GOLDMAN & CO LP	0%	0	-	-270K	-100.00%
Dec 31, 2023	CETERA ADVISORS LLC	0%	0	-	-11.19K	-100.00%
Dec 31, 2023	CUTLER GROUP LLC / CA	0%	0	-	-2.4K	-100.00%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0%	0	-	-15.7K	-100.00%
Dec 31, 2023	NEUBERGER BERMAN GROUP LLC	0%	0	-	-16.07K	-100.00%
Dec 31, 2023	VERITION FUND MANAGEMENT LLC	0%	0	-	-9.06M	-100.00%
Dec 31, 2023	BLACKSTONE INC.	0%	0	-	-1.05M	-100.00%
Sep 30, 2023	BLACKROCK INC.	2.69%	1.87M	3.21M	1.27M	+210.44%
Sep 30, 2023	VELAN CAPITAL INVESTMENT MANAGEMENT LP	7.43%	5.19M	8.87M	0	0
Sep 30, 2023	PFM HEALTH SCIENCES, LP	12.79%	8.92M	15.25M	28.24K	+0.32%
Sep 30, 2023	KINGDON CAPITAL MANAGEMENT, L.L.C.	7.46%	5.2M	8.89M	0	0
Sep 30, 2023	VR ADVISER, LLC	7.61%	5.3M	9.07M	0	0
Sep 30, 2023	VANGUARD GROUP INC	7.98%	5.56M	9.51M	3.2M	+135.31%
Sep 30, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	12.59%	8.78M	15.01M	849.36K	+10.71%
Sep 30, 2023	ALTA WEALTH ADVISORS LLC	0.04%	31.03K	53.06K	0	0
Sep 30, 2023	JUMP FINANCIAL, LLC	0.05%	32.66K	55.85K	32.66K	+100.00%
Sep 30, 2023	GSA CAPITAL PARTNERS LLP	0.05%	33.55K	57K	21.25K	+172.78%
Sep 30, 2023	PRINCIPAL FINANCIAL GROUP INC	0.05%	34.65K	59.26K	2.88K	+9.07%
Sep 30, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.08%	56.13K	95.98K	17.43K	+45.03%
Sep 30, 2023	TWO SIGMA INVESTMENTS, LP	0.08%	56.9K	97.3K	44.8K	+370.25%
Sep 30, 2023	PEAK6 INVESTMENTS LLC	0.09%	64.47K	110.24K	-10K	-13.43%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.11%	75.08K	128.38K	60.34K	+409.51%
Sep 30, 2023	CITIGROUP INC	0.12%	83.12K	142.13K	82.93K	+44,585.48%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.13%	92.61K	158.37K	-60.92K	-39.68%
Sep 30, 2023	ATOM INVESTORS LP	0.15%	102.78K	175.75K	102.78K	+100.00%
Sep 30, 2023	MILLENNIUM MANAGEMENT LLC	0.26%	182.5K	312.07K	-1.07M	-85.37%
Sep 30, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.29%	201.7K	344.91K	100K	+98.33%
Sep 30, 2023	STATE STREET CORP	0.3%	206.56K	353.21K	-4.05K	-1.92%
Sep 30, 2023	J. GOLDMAN & CO LP	0.39%	270K	461.7K	0	0
Sep 30, 2023	MORGAN STANLEY	0.42%	290.21K	496.26K	47.22K	+19.43%
Sep 30, 2023	NORTHERN TRUST CORP	0.42%	296.01K	506.18K	175.51K	+145.65%
Sep 30, 2023	BOOTHBAY FUND MANAGEMENT, LLC	0.65%	453.15K	774.89K	453.15K	+100.00%
Sep 30, 2023	POINT72 ASSET MANAGEMENT, L.P.	14.89%	10.38M	17.76M	-166.22K	-1.58%
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	13.62%	9.5M	16.25M	0	0
Sep 30, 2023	VERITION FUND MANAGEMENT LLC	12.99%	9.06M	15.49M	-1.43M	-13.62%
Sep 30, 2023	UBS OCONNOR LLC	0.84%	583.54K	997.86K	0	0
Sep 30, 2023	CITADEL ADVISORS LLC	0.89%	618.54K	1.06M	-40.67K	-6.17%
Sep 30, 2023	MARSHALL WACE, LLP	0.9%	626.67K	1.07M	626.67K	+100.00%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.91%	632.54K	1.08M	-87.23K	-12.12%
Sep 30, 2023	ALTIUM CAPITAL MANAGEMENT LP	0.93%	650K	1.11M	-775K	-54.39%
Sep 30, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.98%	683.38K	1.17M	-624.15K	-47.73%
Sep 30, 2023	RENAISSANCE TECHNOLOGIES LLC	1.4%	977K	1.67M	321.2K	+48.98%
Sep 30, 2023	72 INVESTMENT HOLDINGS, LLC	1.42%	989K	1.69M	0	0
Sep 30, 2023	BLACKSTONE INC.	1.51%	1.05M	1.8M	0	0
Sep 30, 2023	ALLY BRIDGE GROUP (NY) LLC	1.51%	1.06M	1.81M	-2.14M	-66.99%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	1.65%	1.15M	1.97M	-950K	-45.24%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.86%	1.3M	2.22M	854.9K	+192.85%
Sep 30, 2023	ACADIAN ASSET MANAGEMENT LLC	2.06%	1.43M	2.45M	-108.74K	-7.05%
Sep 30, 2023	VIDA VENTURES ADVISORS, LLC	2.11%	1.47M	2.51M	0	0
Sep 30, 2023	CIBC ASSET MANAGEMENT INC	2.62%	1.83M	3.12M	295.43K	+19.30%
Sep 30, 2023	BAKER BROS. ADVISORS LP	2.7%	1.88M	3.21M	0	0
Sep 30, 2023	IKARIAN CAPITAL, LLC	3.23%	2.25M	3.85M	2.25M	+100.00%
Sep 30, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	5.9%	4.12M	7.04M	641.76K	+18.46%
Sep 30, 2023	BANK OF AMERICA CORP /DE/	5.98%	4.17M	7.13M	-281.07K	-6.31%
Sep 30, 2023	ACUTA CAPITAL PARTNERS, LLC	6.43%	4.49M	7.67M	235K	+5.53%
Sep 30, 2023	SPHERA FUNDS MANAGEMENT LTD.	6.95%	4.85M	8.29M	-3.91M	-44.66%
Sep 30, 2023	TRI LOCUM PARTNERS LP	6.96%	4.86M	8.3M	-28.84K	-0.59%

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 24, 2026	DESIMONE JILL	SALE	315.70	837	264.25K	2.34K
Nov 20, 2025	MASTROCOLA LAUREN	SALE	192.71	2.15K	413.37K	10.44K
Nov 20, 2025	NEMIROFF ALEX	SALE	194.30	9.1K	1.77M	20.83K
Oct 16, 2025	ADAGE CAPITAL MANAGEMENT, L.P.	SALE	140.00	19.2K	2.69M	2.06M
Nov 14, 2024	NEMIROFF ALEX	SALE	80.20	8.24K	660.83K	10.3K
Nov 14, 2024	MASTROCOLA LAUREN	SALE	81.78	5.19K	424.32K	5.61K
Oct 05, 2023	DESIMONE JILL	PURCHASE	1.75	14.5K	25.38K	14.5K
Jun 27, 2023	SOUZA MARCIO	PURCHASE	1.06	10K	10.59K	45K
Mar 24, 2023	MITCHELL DEAN J	PURCHASE	0.84	50K	41.82K	75K
Mar 24, 2023	KELLY TIMOTHY EDWIN	PURCHASE	0.87	8K	7K	46.42K
Mar 23, 2023	SOUZA MARCIO	PURCHASE	0.86	35K	30.21K	35K
Jun 16, 2022	MASTROCOLA LAUREN	PURCHASE	1.93	3K	5.78K	31.39K
Jun 13, 2022	NEMIROFF ALEX	PURCHASE	1.63	7.5K	12.23K	39.35K
Jun 09, 2022	KELLY TIMOTHY EDWIN	PURCHASE	1.76	10K	17.65K	40.49K
Jun 08, 2022	MITCHELL DEAN J	PURCHASE	1.81	25K	45.19K	25K
Jun 08, 2022	SOUZA MARCIO	PURCHASE	1.85	27K	49.89K	189.18K
Oct 06, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	17.50	400K	7M	0
Oct 05, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	19.15	23.95K	458.57K	400K
Oct 01, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	19.13	22.6K	432.34K	423.95K
Aug 31, 2021	KELLY TIMOTHY EDWIN	PURCHASE	19.48	3.91K	76.07K	3.91K
Aug 23, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	20.04	771	15.45K	446.55K
Aug 18, 2021	SOUZA MARCIO	PURCHASE	15.79	9.54K	150.67K	86.79K
Aug 18, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	15.88	3K	47.64K	798.94K
Aug 12, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	13.92	10.06K	140.04K	801.94K
Aug 11, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	15.03	17.22K	258.85K	812K
Aug 03, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	14.99	22.3K	334.28K	829.22K
Aug 02, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	15.78	40K	631.2K	851.52K
Jul 30, 2021	BSOF PARALLEL MASTER FUND L.P.	SALE	15.68	15.85K	248.59K	891.52K
Nov 10, 2020	SOUZA MARCIO	PURCHASE	26.08	3.85K	100.3K	24.45K
Oct 20, 2020	VITOROVIC STEFAN	PURCHASE	19.00	250K	4.75M	2.94M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES8371

NET SHARES-8371

SHARES HELD2.34K1

% NET SHARES-135.82%0%

Frequently Asked Questions