ENSC Company Profile and Key Details

Q: Who are the executives of ENSC?

Mr. David C. Humphrey C.P.A.Chief Financial Officer, Sec. & TreasurerMr. David C. Humphrey CPAChief Financial Officer, Sec. & TreasurerDr. Jeffrey Millard Ph.d.Chief Operating OfficerMr. Richard Wright M.B.A., MSEChief Bus. OfficerDr. Linda Pestano Ph.D.Chief Devel. OfficerDr. William K. Schmidt Ph.D.Chairman of Clinical Advisory Board & Chief Medical OfficerDr. D. Lynn Kirkpatrick Ph.D.Pres, Chief Executive Officer & DirectorMr. Geoffrey BirkettChief Commercial Officer

NASDAQ : ENSC

Ensysce Biosciences

$0.44

-0.02199999-4.80%

Open: 10:55 AM

68.03

BESG ScoreESG Rating

Profile Key Stats Analyst Ratings Ownership Ratios Financials Dividend & splits Sentiment Forecast

Price Chart

Stock Price Today

Ensysce Biosciences, Inc. (ENSC) stock declined over -4.80%, trading at $0.44 on NASDAQ, down from the previous close of $0.46. The stock opened at $0.45, fluctuating between $0.43 and $0.46 in the recent session.

Stock Snapshot

0.4581

Prev. Close

6.7M

Market Cap

0.4321

Day Low

-0.16

P/E Ratio

-2.76

EPS (TTM)

-4.76

Cash Flow per Share

0.45

Open

15.37M

Number of Shares

0.4582

Day High

107.41%

Free Float in %

-0.29

Book Value

247.49K

Volume

Relevant Articles

SEC Fillings

Current Report (8-k)

Filing Date	Accepted Date

Annual Report (10-k)

Filing Date	Accepted Date

Stock Price History Chart

Date	Open	High	Low	Close	Volume
Sep 18, 2026	0.45	0.46	0.44	0.46	494.68K
Sep 17, 2026	0.45	0.47	0.44	0.45	391.1K
Sep 16, 2026	0.45	0.46	0.43	0.45	381.87K
Sep 15, 2026	0.48	0.48	0.44	0.45	315.87K
Sep 14, 2026	0.49	0.51	0.47	0.48	418.93K
Sep 11, 2026	0.52	0.52	0.48	0.49	561.62K
Sep 10, 2026	0.48	0.53	0.44	0.52	926.93K
Sep 09, 2026	0.48	0.50	0.46	0.47	672.1K
Sep 08, 2026	0.47	0.50	0.40	0.47	1.45M
Sep 04, 2026	0.44	0.46	0.41	0.46	530.34K
Sep 03, 2026	0.44	0.45	0.43	0.44	0
Sep 02, 2026	0.40	0.45	0.38	0.44	1.39M
Sep 01, 2026	0.39	0.39	0.38	0.39	207.68K
Aug 31, 2026	0.39	0.41	0.39	0.39	516.21K
Aug 28, 2026	0.40	0.41	0.39	0.40	486.54K
Aug 27, 2026	0.40	0.41	0.39	0.40	562.68K
Aug 26, 2026	0.41	0.42	0.39	0.41	747.01K
Aug 25, 2026	0.36	0.42	0.36	0.40	1.66M
Aug 24, 2026	0.37	0.37	0.35	0.36	951.15K
Aug 21, 2026	0.37	0.37	0.36	0.37	746.89K

Contact Details

La Jolla, CA 92037

United States

https://www.ensysce.com 858 263 4196

About Company

Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical firm dedicated to developing novel prescription drugs for the treatment of severe pain in the United States, with a specific focus on preventing opioid addiction, misuse, abuse, and overdose. The company leverages two primary technological frameworks: the Trypsin Activated Abuse Protection (TAAP) platform, which creates opioid prodrugs designed to resist abuse, and the Multi-Pill Abuse Resistance (MPAR) platform, engineered to offer protection against overdose through its advanced opioid prodrug technology. Ensysce's pipeline features several key candidates, including PF614, an oxycodone prodrug developed using the TAAP platform, currently undergoing Phase II clinical trials for both acute and chronic pain management. Another product, PF614-MPAR, is a combination of PF614 and nafamostat, in Phase I clinical development to provide overdose protection against excessive oral consumption. Furthermore, the company is exploring an oral and inhaled formulation of nafamostat for potential use against coronaviral infections and other pulmonary diseases, such as cystic fibrosis. The company's development efforts also include PF329, an extended-release hydromorphone prodrug similar to PF614. In the area of ADHD treatment, Ensysce is advancing PF8001 and PF8026, which are extended-release and immediate-release amphetamine prodrugs, respectively, aimed at deterring medication abuse. Additionally, PF26810, an extended-release methadone prodrug, is in development for opioid use disorder. Ensysce Biosciences, Inc. operates from its headquarters in La Jolla, California.

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Company Overview

Ensysce Biosciences, Inc. (NASDAQ:ENSC) closed at $0.44 USD, losing -$0.02 (-4.80%) from the previous close of $0.46. The stock is currently mid-range between its 52-week high and low $0.23 and $2.75. With a market capitalization of about $6.70 million, Ensysce Biosciences, Inc. is classified as a micro-cap and shows market-like volatility (beta ~0.98). Key stats such as the average daily volume over the past year has been around 14.50 million shares, volume is running light vs its 52-week average. Headquartered in La Jolla, CA, Ensysce Biosciences, Inc. operates in the Healthcare sector and the Biotechnology industry. Led by CEO D. Lynn Kirkpatrick, the company employs approximately 9 people and listed since March 14, 2018. Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical firm dedicated to developing novel prescription drugs for the treatment of severe pain in the United States, with a specific focus on preventing opioid addiction, misuse, abuse, and overdose.

Technical Performance

ENSC has shown mixed momentum, gaining 3.75% over the past week and -60.55% over the past quarter, though year-to-date performance is up 2.07%. Short-term trend indicators are bullishly aligned (SMA20 -18.87%, SMA50 -50.29%, SMA200 -77.96%). The stock’s 14-day RSI is 30.24 (weak momentum), while the ATR of 0.09 points to higher daily volatility. The stock remains hovering near 52-week lows, trading -93.09% below its high and over 25.64% above its low. Average 10-day trading volume of 427.35 thousand shares is below the 3-month average of 13.93 million, indicating normal recent market interest.

Valuation Metrics

Ensysce Biosciences, Inc. trades at a P/E ratio of -0.17, slightly below the S&P 500 average, with a price-to-sales ratio of 6.05 and a price-to-book ratio of -7.64 indicating negative book value, which may reflect financial stress. The P/FCF stands at -0.78, also above market averages.

Dividend & Fair Value

Ensysce Biosciences, Inc. last paid a dividend of 0 per share, Dividend and splits history remains an important factor for investors monitoring long-term returns. A discounted cash flow model estimates fair value at around $0.16. This means the shares are trading above this model’s fair value.

Earnings & Analyst Outlook

The latest quarter delivered EPS of -$0.20. The next quarter is forecast at -$1.26. Next year's EPS is expected at $40.44. Ensysce Biosciences, Inc. earnings surprise history is frequent misses against expectations. The quarter that ended August 13, 2026, missed forecasts by -60.0%. The prior quarter beat by -28.77%. Over the last six quarters, Apple has recorded several small beats. These include -53.97% in May 13, 2025.

Shareholding & Insider Activity

Ensysce Biosciences, Inc. has 19.46 million shares outstanding. The public float is 19.44 million shares, elevated short interest at 1.25% of float. This equals 191.29 thousand shares. The short ratio is 0.16 days. Institutional investors hold 3.32% of the float. Insiders own 0.06%. HG Vora Capital Management, LLC holds 3.84 million shares, GOWER BOB G has 916.74 thousand shares and Kirkpatrick Lynn has 381.85 thousand shares. Over the past six months, insider transactions show net buying. They sold 0.00 shares across 0 transactions.

Financial & Profitability Overview

Over the trailing twelve months, Ensysce Biosciences generated $2.23M in revenue, or $0.99 per share. Gross margin was -240.17%, operating margin -480.52%, and net profit margin -476.39%. Returns are negative, with ROA at -392.38% and ROE at 1631.59%.
On valuation metrics, Ensysce Biosciences trades at a P/E of -0.17, P/S of 6.05 and P/B of -7.64. Liquidity is tight, with a current ratio of 0.70 and quick ratio of 0.70. Operationally, the company’s inventory turnover is 0.00 and cash conversion cycle is 130.67 days. Debt-to-equity is -0.25, supported by a cash flow-to-debt ratio of -44.99.

Quarterly Financial Highlights

For the quarter ended Dec 31, 2023, Ensysce Biosciences posted revenue of $2.23M, down slightly from $0.00 in the prior quarter. Gross profit was - $5.36M (margin -240.17%). Operating income was - $10.72M (margin -480.5%). Net income was- $10.63M (EPS - $4.69).
The company ended the quarter with $1.12M in cash and short-term investments, a total debt of $854.70K, and net debt of - $268.91K. Total assets were $2.71M, with equity of - $979.68K. Financials further reflected weakness, with operating cash flow of - $10.78M, free cash flow of - $10.78M, and capital expenditures of $0.00.

Price Forecast & Outlook

Our AI price prediction model suggests that Ensysce Biosciences, Inc. stock has strong potential for upside but may face short-term weakness followed by gains in the medium and long term. 2-Week Outlook: Projected increase of 4.78%, with price expected at $0.48 by October 02, 2026, within a range of $0.42 to $0.55 3-Month Outlook: Projected fall of -82.54%, reaching $0.08 by December 17, 2026, with a range of $0.02 to $0.13. 1-Year Outlook: Projected loss of -97.82%, with price at $0.01 by September 17, 2027, within a range of $0.00 to $0.34.

Key Takeaways

Ensysce Biosciences, Inc. (NASDAQ:ENSC) shares are flat 2.07% year-to-date currently trading near 52-week highs band. Short-term momentum has been negative over the last quarter, despite recent volatility. Valuation shows Ensysce Biosciences, Inc. trading at a premium to the broader market with a P/E of -0.17. Analyst sentiment is bullish, with the majority of ratings in Buy territory and a mean price target of $7.50, suggesting 1537.2% upside. Our AI forecast model points to short-term strength (4.78% over two weeks), a medium-term fall (-82.54% over three months), and a longer-term loss (-97.82% over one year), with expected trading ranges indicating moderate volatility.

Frequently Asked Questions

What is the current Ensysce Biosciences, Inc. (ENSC) stock price?

Ensysce Biosciences, Inc. (NASDAQ: ENSC) stock price is $0.44 in the last trading session. During the trading session, ENSC stock reached the peak price of $0.46 while $0.43 was the lowest point it dropped to. The percentage change in ENSC stock occurred in the recent session was -4.8% while the dollar amount for the price change in ENSC stock was - $0.02.

ENSC's industry and sector of operation?

The NASDAQ listed ENSC is part of Biotechnology industry that operates in the broader Healthcare sector. Ensysce Biosciences, Inc. designs, manufactures, and markets smartphones, personal computers, tablets, wearables, and accessories worldwide.

Who are the executives of ENSC?

Mr. David C. Humphrey C.P.A.
Chief Financial Officer, Sec. & Treasurer
Mr. David C. Humphrey CPA
Chief Financial Officer, Sec. & Treasurer
Dr. Jeffrey Millard Ph.d.
Chief Operating Officer
Mr. Richard Wright M.B.A., MSE
Chief Bus. Officer
Dr. Linda Pestano Ph.D.
Chief Devel. Officer
Dr. William K. Schmidt Ph.D.
Chairman of Clinical Advisory Board & Chief Medical Officer
Dr. D. Lynn Kirkpatrick Ph.D.
Pres, Chief Executive Officer & Director
Mr. Geoffrey Birkett
Chief Commercial Officer

How ENSC did perform over past 52-week?

ENSC's closing price is 99.17% higher than its 52-week low of $0.23 where as its distance from 52-week high of $2.75 is -83.34%.

How many employees does ENSC have?

Number of ENSC employees currently stands at 9.

Link for ENSC official website?

Official Website of ENSC is: https://www.ensysce.com

How do I contact ENSC?

ENSC could be contacted at phone 858 263 4196 and can also be accessed through its website. ENSC operates from 7946 Ivanhoe Avenue, La Jolla, CA 92037, United States.

How many shares of ENSC are traded daily?

ENSC stock volume for the day was 247.49K shares. The average number of ENSC shares traded daily for last 3 months was 14.5M.

What is the market cap of ENSC currently?

The market value of ENSC currently stands at $6.70M with its latest stock price at $0.44 and 15.37M of its shares outstanding.

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Employees	9
Beta	0.98
Sales or Revenue	$2.23M
5Y Sales Change%	0%
Fiscal Year Ends	December
Sector	Healthcare
Industry	Biotechnology

ENSC Company Profile and Key Details

Ensysce Biosciences

Price Chart

Stock Price Today

Stock Snapshot

Relevant Articles

SEC Fillings

Current Report (8-k)

Annual Report (10-k)

Stock Price History Chart

Contact Details

About Company

Company Information

Stock Peers

Company Overview

Technical Performance

Valuation Metrics

Dividend & Fair Value

Earnings & Analyst Outlook

Shareholding & Insider Activity

Financial & Profitability Overview

Quarterly Financial Highlights

Price Forecast & Outlook

Key Takeaways

Frequently Asked Questions

Financial & Profitability Overview

Quarterly Financial Highlights

Shareholding & Insider Activity

Earnings & Analyst Outlook

Technical Performance

Company Overview

Valuation Metrics

Dividend & Fair Value

Price Forecast & Outlook

Key Takeaways