SYBX Company Profile and Key Details

Synlogic, Inc. has 11.70 million shares outstanding. The public float is 3.61 million shares, elevated short interest at 0.77% of float. This equals 40.92 thousand shares. The short ratio is 0.38 days. Institutional investors hold 68.23% of the float. Insiders own 15.65%. Sofinnova Venture Partners VIII, L.P. holds 2.97 million shares, POWELL MICHAEL has 2.97 million shares and BASKETT FOREST has 2.97 million shares. Over the past six months, insider transactions show net buying. They sold 0.00 shares across 0 transactions.

SYBX has shown weak momentum, losing -50.44% over the past week and -69.4% over the past quarter, though year-to-date performance is down -50.0%. Short-term trend indicators are bullishly aligned (SMA20 -50.55%, SMA50 -56.75%, SMA200 -59.09%). The stock’s 14-day RSI is 16.28 (weak momentum), while the ATR of 0.1 points to higher daily volatility. The stock remains sitting in the mid-range of its 52-week band, trading -71.43% below its high and over 0.0% above its low. Average 10-day trading volume of 8.90 thousand shares is below the 3-month average of 79.95 thousand, indicating normal recent market interest.

Synlogic, Inc. (OTC:SYBX) closed at $1.22 USD, gaining $0.07 (6.09%) from the previous close of $1.15. The stock is currently mid-range between its 52-week high and low $0.54 and $1.87. With a market capitalization of about $14.27 million, Synlogic, Inc. is classified as a micro-cap and shows lower-than-market volatility (beta ~0.50). Key stats such as the average daily volume over the past year has been around 73.07 thousand shares, volume is running light vs its 52-week average. Headquartered in Winchester, MA, Synlogic, Inc. operates in the Healthcare sector and the Biotechnology industry. Led by CEO Mary Beth Dooley, the company employs approximately 1 people and listed since September 30, 2015. Synlogic, Inc. does not have significant operations.

Synlogic, Inc. generated EPS of -$0.27 over the past year. Five-year average earnings growth is 40.39%. The latest quarter delivered EPS of $0.12. The next quarter is forecast at $nan. Next year's EPS is expected at $21.84. Synlogic, Inc. earnings surprise history is a mixed track record. The quarter that ended March 12, 2026, missed forecasts by -233.33%. The prior quarter beat by 72.73%. Over the last six quarters, Apple has recorded several small beats. These include -94.44% in November 12, 2024.

Synlogic, Inc. last paid a dividend of 0 per share, Dividend and splits history remains an important factor for investors monitoring long-term returns. A discounted cash flow model estimates fair value at around $1.19. This means the shares are trading near this model’s fair value.

Synlogic, Inc. trades at a P/E ratio of -22.72, slightly below the S&P 500 average, with a price-to-sales ratio of 0.0 and a price-to-book ratio of 1.26 suggesting the stock is closer to book value. The P/FCF stands at -3.71, also below market averages.

Synlogic, Inc. (NASDAQ:SYBX) shares are down -50.0% year-to-date currently trading near 52-week highs band. Short-term momentum has been negative over the last quarter, despite recent volatility. Valuation shows Synlogic, Inc. trading at a premium to the broader market with a P/E of -22.72. Analyst sentiment is bullish, with the majority of ratings in Buy territory and a mean price target of $9.39, suggesting 669.67% upside. Our AI forecast model points to short-term strength (9.02% over two weeks), a medium-term rise (48.36% over three months), and a longer-term gain (76.23% over one year), with expected trading ranges indicating moderate volatility.

Our AI price prediction model suggests that Synlogic, Inc. stock has strong potential for upside but may face short-term weakness followed by gains in the medium and long term. 2-Week Outlook: Projected increase of 9.02%, with price expected at $1.33 by September 24, 2026, within a range of $1.18 to $1.50 3-Month Outlook: Projected rise of 48.36%, reaching $1.81 by December 09, 2026, with a range of $1.71 to $1.90. 1-Year Outlook: Projected gain of 76.23%, with price at $2.15 by September 10, 2027, within a range of $0.00 to $0.00.