Stock Forecast Chart
Stock Price Prediction Summary
Forecast Score Based on 2 Weeks
Based on our forecast, the price of KPTI will decline by -88.52% over the next 2 Weeks and hit $0.19 by Wednesday, September 23, 2026. In that time frame, KPTI's share price is expected to range between $0.00 and $1.96.
BearishAverageBullish| Date | Predicted Lower | Predicted | Predicted Upper |
|---|---|---|---|
| Sep 23, 2026 | 0.00 | 0.19 | 1.96 |
| Sep 22, 2026 | 0.00 | 0.04 | 1.73 |
| Sep 21, 2026 | 0.00 | 0.01 | 1.77 |
| Sep 18, 2026 | 0.00 | 0.35 | 2.15 |
| Sep 17, 2026 | 0.00 | 0.99 | 2.85 |
| Sep 16, 2026 | 0.00 | 0.99 | 2.78 |
| Sep 15, 2026 | 0.00 | 0.84 | 2.69 |
| Sep 14, 2026 | 0.00 | 0.81 | 2.49 |
| Sep 11, 2026 | 0.00 | 1.15 | 3.07 |
| Sep 10, 2026 | 0.08 | 1.79 | 3.63 |
KPTI shares fell -4.14% in Thursday, September 10, 2026's trading session, dropping from a previous close of $1.69 to move at $1.62. The stock demonstrated notable intraday movement (see KPTI's key stats for a full breakdown), fluctuating between $1.60 and $1.68, a +5.33% trading range. While recent weeks have seen some volatility, KPTI has managed to secure a -16.49% drop over the past 2 weeks. The downward price movement was accompanied by increased trading volume, with approximately 798.44K shares changing hands, 26.58K more than the previous session. This amounted to $1.29M in total market activity.
Will KPTI Continue Its Upward Trend?
According to analyst ratings and projections for KPTI, Karyopharm Therapeutics Inc. shares are anticipated to increase by +17.27%, potentially reaching $1.96 per share by September 23, 2026. Short-term technical indicators for KPTI currently suggest a bearish sentiment. This aligns with the stock's recent performance, as it has recorded 17 negative trading days within the past 30 sessions. Based on the KPTI stock forecast, now is a good time to buy KPTI stock because its current trading price is +735.05% above our predicted value, hinting at a possible undervaluation. For deeper insights, view our sentiment analysis on KPTI covering social and institutional perspectives.
KPTI Technical Momentum: Overbought, Oversold, or Neutral?
An analysis of Relative Strength Index (RSI) indicators provides insight into KPTI's momentum. Short-term RSIs (9, 14, and 20-day figures ranging from 25.54% to 26.93%) suggest the stock is in a strong bearish momentum phase. The 50-day RSI, at 35.58%, hints at potential weakness developing in the medium term. Meanwhile, the 100-day RSI, at 41.73%, maintains a neutral outlook for the long term. Insights into KPTI's shareholder base show how institutional investors are positioning themselves during these momentum shifts
Karyopharm Therapeutics Short-Term Forecasts
KPTI Forecast For Next 5 Days
Our algorithm anticipates Karyopharm Therapeutics (KPTI) stock could hit $0.86 by Sep 17, 2026. This represents a -46.93% fall from today's price, following a -27.39% change over the past five days.
KPTI Forecast For Next 30 Days
Based on analysis of market trends, the outlook for Karyopharm Therapeutics Inc. (KPTI) stock over the next 30 days is largely negative. Price forecasts suggest an average target of $0.55, which would mean a -66.05% decrease from the current price of $1.62. Projections for this period range from a high of $2.62 to a low of $0.00.
KPTI Forecast For Next 90 Days
Our proprietary market analysis suggests predictions for Karyopharm Therapeutics's price over the next three months point to a rise. KPTI stock is expected to peak at $4.97 on Sep 30, 2026 before potentially dipping to $0.14 on Oct 30, 2026. On average, KPTI is likely to trade around $2.78 in the coming 90 days.
Karyopharm Therapeutics Stock Forecast 2025
Based on our predictive models, Karyopharm Therapeutics (KPTI) is expected to trade between $0.14 and $4.97 throughout 2026. This would result in an average price of $2.83, potentially offering investors a +74.69% return from current levels.
Karyopharm Therapeutics Inc. Monthly Forecast 2026–2027
September 2026
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in September 2026. The price is predicted to move between $2.46 and $4.97, settling at an average of $3.99. This could translate to a +146.30% gain.
October 2026
Based on current market signals, Karyopharm Therapeutics Inc. is projected to trend october 2026. We forecast a trading range from $0.14 to $4.95, with a likely average price of $2.47. Investors could expect a potential return of +52.47%.
November 2026
Our predictive algorithms indicate Karyopharm Therapeutics Inc. stock may see a shift in November 2026. The expected range spans $0.20–$3.71, with an average target of $2.13. This represents a positive outlook and a possible gain of +31.48%.
December 2026
Analyzing established trends, Karyopharm Therapeutics Inc. looks set to move in December 2026. Projections place the stock between $1.59 and $4.03, averaging around $3.05. This suggests a +88.27% gain from current levels.
January 2027
Market indicators suggest Karyopharm Therapeutics Inc. could experience notable changes during January 2027. Prices could fluctuate within $0.61 to $3.33, with a midpoint forecast of $1.68. The stock might deliver a +3.70% gain.
February 2027
Forecasting for February 2027, models estimate that Karyopharm Therapeutics Inc. may undergo key fluctuations. If trends hold, the stock might trade between $2.24 and $6.27, averaging $4.87. This signals a positive trajectory with potential returns around +200.62%.
March 2027
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in March 2027. The price is predicted to move between $1.83 and $5.69, settling at an average of $4.25. This could translate to a +162.35% gain.
April 2027
Based on current market signals, Karyopharm Therapeutics Inc. is projected to trend april 2027. We forecast a trading range from $1.83 to $5.46, with a likely average price of $4.72. Investors could expect a potential return of +191.36%.
May 2027
Our predictive algorithms indicate Karyopharm Therapeutics Inc. stock may see a shift in May 2027. The expected range spans $0.38–$5.54, with an average target of $4.95. This represents a positive outlook and a possible gain of +205.56%.
June 2027
Analyzing established trends, Karyopharm Therapeutics Inc. looks set to move in June 2027. Projections place the stock between $0.00 and $3.56, averaging around $3.47. This suggests a +114.20% gain from current levels.
July 2027
Market indicators suggest Karyopharm Therapeutics Inc. could experience notable changes during July 2027. Prices could fluctuate within $0.00 to $3.36, with a midpoint forecast of $3.45. The stock might deliver a +112.96% gain.
August 2027
Forecasting for August 2027, models estimate that Karyopharm Therapeutics Inc. may undergo key fluctuations. If trends hold, the stock might trade between $0.00 and $2.28, averaging $1.62. This signals a positive trajectory with potential returns around 0.
September 2027
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in September 2027. The price is predicted to move between $0.00 and $1.63, settling at an average of $1.63. This could translate to a +0.62% gain.
KPTI's history of dividends and stock splits also plays a role in long-term investor confidence.